Ali Zaib Blood arranges blood camps at various Colleges, Factories, Public places, etc. for the collection of blood for the Thalassaemic and Hemophilic Patients. The volunteer donors are screened for the serious diseases like Hepatitis B, Hepatitis C, HIV, Malaria syphilis etc. before the blood collection.
Ali Zaib Blood is providing its 24/7 services to the patients in six major cities of Punjab province through its transfusion centers. Thousands of patients are being provided free of cost blood transfusion facilities every month. The organization provides a pleasant patients friendly environment and air conditioned transfusion rooms. Its laboratory is equipped with all necessary innovative equipments where the pathologists and laboratory technicians are following standard operating procedures aiming at the provision of safe blood and reliable medical investigations which is necessary to ensure proper treatments of the patients. Highly qualifies staff serve the patients with the passion to redress the grievances of the patients.
The blood bank of Ali Zaib Blood is fully equipted with highly qualified staff alongwith innovative blood screening, processing and storage machanism that ensures the availablity of safe blood to the patients. Blood and its componets such as Packed Red Cells, Fresh Frozen Plasma (FFP), Platelets and Crioprecipitates are available 24/7 at the blood bank. This facility is available for all the patients regadless of disease and the hospital where the patients have been treated.
A large number of patients from small cities and rural areas approach Ali Zaib Foundation for medical treatment and blood transfusion facilities every day. In an attempt to redress their grievances, Ali Zaib Foundation is providing them with transport facilities from Bus stop and railway Stations to its blood transfusion center at zero cost.
In an attempt to spread awareness about Thalassaemia, and Hemophila, Ali Zaib Foundation organizes awareness walks and seminars in various cities. It also arrange awareness workshops at Universities, Colleges and Technical & Vocational Training Institutes so that the youth of the nation could be aware of these serious diseases.
In Pakistan Ali Zaib Foundation is one of the largest group of non-profited organization they serve the children who suffered from hemophilia and today is a Hemophilia Centre in Pakistan.
Hemophilia may be a rare hemorrhage disorder that stops the blood from coagulates properly; therefore an individual who has it bleeds over somebody without haemophilia does. It is a hereditary condition, which implies it's the result of a modification in genes that was either familial or occurred throughout development within the female internal reproductive organ. The normal mechanism for coagulation could be a complicated series of events involving the interaction of the injured vessel, blood cells (called platelets), and over twenty completely different proteins that additionally circulate within the blood.
When a vessel is out of action during an approach that causes harm, platelets collect over the injured space, and form a brief plug to forestall additional harm. This temporary plug, however, is simply too disorganized to function a semi permanent solution, thus a series of chemical events occur, leading to the formation of a more reliable plug. The ultimate plug involves tightly woven fibers of a fabric known as protein. The assembly of protein needs the interaction of many chemicals, particularly a series of proteins known as clotting factors. A minimum of 13 completely different clotting factors are known.
In general, someone with milder bleeder's disease might only bleed excessively once during a while, whereas severe bleeder's disease puts somebody at risk for having hemorrhage issues rather more typically. Most of the peoples with hemophilia discover they need the condition once they are babies or young once when they. Generally the disorder is thus mild that a bloke does not even recognize he has it till he has surgery like obtaining his tonsils or appendix out and it's found in blood tests that doctors perform before surgery.
There is lot of tests to available to determine under discrete conditions the length of your time it takes to provide certain parts of the ultimate protein clot. Tests referred to as assays also can determine the proportion of genes VIII and IX present compared to traditional percentages. This info will facilitate in demonstrating the sort of blood disease present, moreover as severity. Individuals with a case history of blood disease could have the benefit of counseling before deciding to have a baby. Families with a positive history of blood disease also can have tests done throughout a gestation to see whether or not the vertebrate may be a diseased person. The test known as chorionic villous sampling examines proteins for the defects that result in blood disease. This test that is related to a tenth risk of miscarriage may be performed at 10-14 weeks. The test referred to as prenatal diagnosis examines the deoxyribonucleic acid of foetal cells shed into the humor for genetic mutations. Prenatal diagnosis that is related to a one in two hundred risk of miscarriage is performed at 15-18 weeks gestation.
TREATMENT
The most vital issue that people with sex-linked disorder will do to stop complications of this disease is to avoid injury. Those people who need dental work or any surgery may have to be pre-treated with an infusion of coagulation factor to avoid hemorrhage. Also, hemophiliacs ought to be unsusceptible against liver disease. Medications that promote injury, like salicylate, ought to be avoided. Various varieties of factors VIII and IX are accessible to interchange a patient's missing factors. These are administered intravenously (directly into the patient's veins Hemophilia A and B are each caused by a genetic disorder gift on the sex chromosome. Close to seventieth of individuals with unwellness or B transmitted the disease, whereas the remaining half-hour have bleeder's disease thanks to a spontaneous mutation. (Illustration by Electronic Illustrators cluster by needle). These issue preparations is also obtained from one donor, by pooling the donations of as several as thousands of donors, or by laboratory creation through extremely advanced genetic techniques. The frequency of treatment with factors depends on the severity of the individual patient's illness. Patients with comparatively delicate illness can solely need treatment within the event of injury, or to arrange for scheduled surgical or dental procedures. Patients with a lot of severe illness would force regular treatment to avoid spontaneous injury. While acceptable treatment of bleeder's disease will each decrease suffering and be life-saving, complications related to treatment may also be quite serious. Concerning 2 hundredth of all patients with hemophilia begin to provide chemicals in their bodies that speedily destroy infused coagulation factor. The presence of such a chemical might greatly hamper efforts to stop or stop a serious hemorrhage.
Both types of Hemophilia A and B are caused by a hereditary imperfections present on the X DNA. (Hemophilia C is innate in an unusual manner.) Regarding 70 percent of all citizens with hemophilia type A or hemophilia type B innate the disease. Other 30 percent extend from an impulsive hereditary transmutation. The consequent concepts are imperative to understanding the heritage of these disorders. All humans have two DNAs determining their sexual category: The difference between males and females with respect to chromosomes is XY and XX respectively. Since the part of chromosome also known as trait is accepted only on the X chromosome, it is also known as "sex-linked chromosome" The chromosome's defective unit is referred to the factor. Both genes 1st are factor VIII and 2nd is factor IX are formed by hereditary faults of the X chromosome, so both types of hemophilia are sex linked. Since a feminine kid all the time receives two X DNAs, she almost always will be given at least one usual X DNA. Consequently, even if she receives one defective X chromosome, she still competent to produce an enough amount of factors c and IX to evade the signs of hemophilia. An individual who has one defective DNA and this person has not suffered from hemophilia its mean he is carrier. He carries the defected gene and can transfer it on to his children. If, yet, he has a son who receives his defective X DNA, he will not be capable to make the right amount of genes VIII or IX, and he will also endure some types of hemophilia.
In the case of severe blood disease, the primary hemorrhage event sometimes happens before eighteen months older. In some babies, blood disease is suspected directly, once a routine circumcision (removal of the foreskin of the penis) ends up in remarkably serious hemorrhage. Toddlers are at explicit risk, as a result of the fall often, and will bleed into the soft tissue of their arms and legs. These little bleeds end in bruising and noticeable lumps, however do not sometimes would like treatment. As a baby becomes a lot of active, hemorrhage could occur into the muscles; a way a lot of painful and enervating downside. These muscles bleeds end in pain and pressure on the nerves within the space of the bleed. Harm to nerves will cause symptom and attenuate ability to use the gashed limb.